Louie est un enfant de 8 ans, vivant dans la ville fictive de Cedar Knoll, dans le Wisconsin. C'est un jeune garçon très sensible et impressionnable, mais aussi intelligent. Il utilise souvent son sens de l'humour pour faire face aux situations difficiles.
Louie, upset with being cast as the Turkey every year, single-handedly ruins the annual Cedar Knolls Elementary Thanksgiving Pageant. The principal decides that as punishment Louie needs to give a presentation on the meaning of Thanksgiving the Monday after the Thanksgiving holiday weekend. Louie tries to figure out the meaning of the holiday while his house is flooded with guests for Thanksgiving dinner, each of whom have their own unique interpretation of the holiday.