Dans son propre rôle de comique, le bavard Jerry Seinfeld mène une vie qui ne le gâte pas tout le temps, notamment à cause des femmes. Avec son collaborateur malhonnête et son voisin loufoque, Jerry analyse toutes les petites choses du quotidien et les absurdités de la société.
While doing his stand up act, Jerry takes questions from the crowd. One of the questions is "where did the series come from?" An often asked question, Jerry responds by showing a videotape he's prepared. The video includes his first appearance on "The Tonight Show" (6 May 1981), interviews with his managers, his co-creator Larry David, executives from NBC and Castle Rock, his fellow cast mates, and other people involved with the production during the early years (the pilot through season. All of this is interspersed with numerous clips from the show. At the end when asked if they are going to do a reunion show, Jerry answers "Ah yes, you've just saw it, I hope you enjoyed it." This is followed by several bloopers.